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Oxford Biomarker Services (OBS) provides pertinent protein biomarker information involving either biomarker assay development or biomarker discovery through a range of different techniques.
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ASSAY DEVELOPMENT SERVICES
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MRM Assays & Absolute Quantitation
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Single & Multiplexed Antibody Assays
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OBS constructs and routinely performs MRM based assays for customers. This technique is quick, sensitive and permits absolute quantitation of protein biomarkers without the need for an antibody.
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OBS develops single and multiplexed antibody assays on protein biomarkers of your choice. These assays are typically used in drug development or diagnostic programs.
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BIOMARKER DISCOVERY SERVICES
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LC-MS Label Free Peptide Profiling
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iTRAQ™ Analysis
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LC-MS comparative peptide profiling is a powerful and sensitive technique for biomarker discovery and subsequent biomarker identification is conducted using LC-MS/MS techniques.
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OBS offers the use of 8plex and 4plex iTRAQ reagents for biomarker discovery and simultaneous protein identification.
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2D Gel Electrophoresis
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DECIDER Database
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OBS offers 2D gel electrophoresis in order discover biomarkers. Differentially expressed proteins can then be identified by MS/MS analysis
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The DECIDER database plays a crucial role in biomarker discovery projects and is derived from the world’s largest source of proprietary proteomics data.
This enables us to select the most robust biomarkers that are specific to certain conditions or diseases whilst eliminating non-specific proteins.
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